Human il-2 uniprot
WebIL-2, Human Interleukin-2 (IL-2) is a Oglycosylated, four α-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. WebUseful information about the gene from Entrez. The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This p rotein binds …
Human il-2 uniprot
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WebInterleukin-2 (IL-2) is an α-helical cytokine belonging to T-helper cell type 1. It has a molecular weight of 15kDa. The IL2 gene is mapped to human chromosome 4q27. IL-2 …
WebProduct name Recombinant human IL-2 protein (Active) See all IL-2 proteins and peptides Biological activity The ED 50 as determined by the dose-dependent stimulation of murine CTLL-2 cells is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10 5 units/mg. Purity > 95 % SDS-PAGE. Endotoxin level < 1.000 Eu/µg Expression system WebOct 3, 2006 · Function. Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal …
WebIL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The … WebDescription Product name Recombinant human IL-2 protein (Active) See all IL-2 proteins and peptides Biological activity The ED50, as determined by the dose-dependent stimulation of murine CTLL-2 cells, is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg. Purity >= 98 % SDS-PAGE. >=98% HPLC analyses. Sterile filtered.
WebUniProt ID (Human) Q9HBE4. ... Human IL-21 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human IL-21 in a sandwich ELISA format. Using the ELISA protocol, the recommended microplates, reagents and solutions, the components supplied in this kit are sufficient to …
WebDescripción general. Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. example of health related fitness exerciseWebMay 23, 2024 · Cryo-EM structures of 11-2 F / MTA-bound human PRMT5/MEP50 complex and its apo form resolved at 3.1 and 3.2 Å respectively show that 11-2 F in the catalytic pocket shifts the cofactor-binding pocket away by ~2.0 Å, contributing to positive cooperativity. ... 2.1.1.320: UniProt & NIH Common Fund Data Resources: Find proteins … example of health promotion activitiesWebHuman IL-2 Protein (PHC0027) in FN. THP-1 cells were treated with 20 ng/mL of human IL-2 recombinant protein ( Product # PHC0023) for 24 hours. Western blot was performed … bruno stairlift beepingWebJul 2, 2002 · 1M47 Crystal Structure of Human Interleukin-2 PDB DOI: 10.2210/pdb1M47/pdb Classification: CYTOKINE Organism (s): Homo sapiens Expression System: Escherichia coli BL21 Mutation (s): No Deposited: 2002-07-02 Released: 2002-07-31 bruno stair chair lift priceWebApr 9, 2024 · This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine … bruno stairlift beep codesWebHuman IL-2 acts on murine and human T cells, and its receptors are shared by others cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ … bruno stairlift battery replacementWebHuman IL-2 acts on murine and human T cells, and its receptors are shared by other cytokines. IL-2Rα is an IL-2–specific receptor, IL-2Rβ is shared with IL-15 and the γ chain that is a common receptor shared by many cytokines including IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. ... IL-2 UniProt View information about IL-2 on UniProt.org ... example of health services