WebApr 12, 2024 · Mutations in glucocerebrosidase (GCase) cause the lysosomal storage disorder Gaucher’s disease and are the most common risk factor for Parkinson’s disease. Using a fusion protein comprising ... WebJul 14, 2010 · Gaucher Disease: Drug: Cerezyme ... The subjects have a diagnosis of Type I Gaucher Disease; Subjects between 2 years old and 75 years old; Subjects documented with glucocerebrosidase deficiency; Subjects with splenomegaly (as indicated by CT volumetric analysis as 5 times over than the standard size (0.2% of total body weight in …
Lysosomal Storage Disorder Treatments - Medical Clinical Policy ... - Aetna
WebImiglucerase is a medication used in the treatment of Gaucher's disease.. It is a recombinant DNA-produced analogue of the human enzyme β-glucocerebrosidase. Cerezyme is a freeze-dried medicine containing imiglucerase, manufactured by Genzyme Corporation.It is given intravenously after reconstitution as a treatment for Type 1 and … Webknown whether CEREZYME® passes via the placenta to the developing fetus. The use of . CEREZYME® in pregnant women with Gaucher disease may be considered only after individual patient risk-benefit assessment has been made. In pregnant Gaucher patients and in those intending to become pregnant, a risk-benefit treatment assessment is … sharonhamm msn.com
Enzyme Replacement Therapy for Gaucher Disease
WebIndication and Usage. Cerezyme ® (imiglucerase) for injection is indicated for treatment of adults and pediatric patients 2 years of age and older with Type 1 Gaucher disease that … WebBusiness Account Executive- Rare Disease, Biotech (23 years) Registered Dietitian (27 years) Certified Diabetes Educator (15 years). ... *Gaucher … WebMay 25, 2024 · Therapy with Cerezyme should be directed by physicians knowledgeable in the management of patients with Gaucher disease. The recommended dosage of Cerezyme based upon disease severity ranges from 2.5 units/kg three times a week to 60 units/kg once every two weeks. For patients weighing 18 kg and greater, infuse the … population trenton new jersey