WebNov 11, 2014 · We focused on CTTN, which has emerged as a key player in aggressive cancers and whether it was responsible for the cancer invasion led by reduced MTSS1 expression. As showed in Fig. 5a and b, CTTN was significantly reduced in MTSS1 overexpressing cells as compared with control. The results reveal that MTSS1 … Web7 Tissue Bank of the National Center for Tumor Diseases (NCT), Heidelberg, Germany. 8 Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer …
CTTN Gene - GeneCards SRC8 Protein SRC8 Antibody
Web钙网蛋白在肿瘤中异常表达的研究进展. 曹繁华. 【摘 要】对于钙网蛋白 (CRT)多方面的研究显示其在大部分种类的疾病中都有异常表达现象,尤其是肿瘤.该文就CRT异常表达与肿瘤发生、发展分子机制及其在不同肿瘤中的研究现状两方面阐述最新进展,总结近几年来 ... WebThe cortactin (CTTN) gene has been found, by transcriptomic profiling, to be overexpressed in pediatric osteosarcoma. The location of CTTN at 11q13 and the role of cortactin in cytoskeleton restructuring make CTTN of interest as a potential biomarker for osteosarcoma. Materials and methods. Osteoblasts were isolated from 20 high-grade osteosarcomas fool toons india
CTTN Overexpression Confers Cancer Stem Cell-like …
WebApr 21, 2024 · CTTN is a major substrate for post translational modifications (PTMs), which are dynamic and reversible processes that regulate functional activities of proteins by the addition or deletion of functional groups [ 2 ]. The major PTMs reported for cortactin are ubiquitination, acetylation, phosphorylation, and glycosylation [ 47, 48, 49 ]. WebDescription: Homo sapiens cortactin (CTTN), transcript variant 2, mRNA. (from RefSeq NM_138565) RefSeq Summary (NM_138565): This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. WebMar 21, 2013 · Cortactin Is a Sensitive Biomarker Relative to the Poor Prognosis of Human Hepatocellular Carcinoma Overexpression of cortactin is closely associated with poor human HCCs prognosis that caused by cancer embolus and metastasis. Cortactin and CTTN should be used for differentiating varieties of survival for patients after HCC resection. electrochemistry potential