WebCDK1 levels were reduced at least twofold in HT2-19 cells cultured in the presence of IPTG compared with the parental HT-1080 cells, and polysomal ribosomes decreased from 43% to 32% ( Fig. 3 F ). CDK1 became barely detectable when HT2-19 cells were kept in the absence of IPTG for 7 d, and polysomal ribosomes decreased further to 18% ( Fig. 3 F ). WebWestern blotting analysis showed that CDK1 protein expression decreased in HepG2 and Hep3B cells after miR-378 mimic transfection compared with NC . Taken together, these results suggested that CDK1 was the target gene of miR-378 and the expression of CDK1 was inhibited by miR-378 in HCC cells.
Myc stimulates cell cycle progression through the …
WebJun 27, 2024 · Cyclin dependent kinase 1 (CDK1) has been primarily identified as a key cell cycle regulator in both mitosis and meiosis. Recently, an extramitotic function of CDK1 emerged when evidence was found that CDK1 is involved in many cellular events that are essential for cell proliferation and survival. I … WebCyclin-dependent kinase 1 (CDK1) is the major protein kinase that drives cells into mitosis (Malumbres, 2014). CDK1 is activated by binding to mitotic cyclins (mainly cyclin B1), … does ultimate bod change with temperature
CDK1 plays an important role in the maintenance of
WebApr 25, 2013 · Figure 2. CDK1 expression in human hepatic cancer tissues and cell lines. (A) The expression levels of CDK1 were determined in 48 pairs of human hepatic cancer tissues (T) and their corresponding … WebCDK1 (CDC2, P34CDC2) is a member of the Ser/Thr protein kinase family. CDK1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S … WebJun 9, 2024 · (C) ULK1 is phosphorylated in nocodazole-arrested mitosis. The 293T cells overexpressing FLAG-tagged mULK1 or GFP were synchronized by single-thymidine and nocodazole. The immunoprecipitates using the FLAG antibody were subjected to Coomassie Brilliant Blue R-250 staining and western blot analysis. does ultimate colon cleanse work