Bap31 hfd
WebHepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice[S] Jia-Lin Xu, Li-Ya Li, Yan-Qing Wang, Ya … WebConditional knockout mice with targeted disruption of BAP31 in adult mouse liver were generated and challenged with a high-fat diet (HFD) for 36 or 96 days, markers of …
Bap31 hfd
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WebJun 26, 2016 · T he protein known as BAP31 was identified by Kim et al. (1994) as a “31 kDa” intracellular membrane component of murine B-lymphocytes that co-purified with membranous immunoglobulin (mIg) D. Recognizing it as a member of the B-lymphocyte receptor-associated protein (BAP) family, which is known to bind mIg molecules in a … WebJan 23, 2007 · Function. Functions as a chaperone protein ( PubMed: 9396746, PubMed: 18287538 ). Is one of the most abundant endoplasmic reticulum (ER) proteins ( PubMed: 9396746, PubMed: 18287538 ). Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated …
WebBAP31-mutant mice. HFD-induced inflammation was aggra-vated in mutant mice, along with increased c-Jun N-terminal kinase and nuclear factor- B activation. These findings … WebJan 13, 2024 · BAP31 is a ubiquitously expressed integral membrane protein of the endoplasmic reticulum. BAP31 is involved in various biological and molecular processes, …
WebSep 15, 2024 · BAP31 could also affect C/EBPβ via modulating IL-4Rα ubiquitination and proteasome degradation in IL-4–stimulated macrophages. Furthermore, we found that BAP31 affects macrophages functions, including angiogenesis and skin fibrosis, during the wound healing process through IL-4Rα, as confirmed by infection with adeno-associated … WebFounded in 1984, today’s HONGFA has become the leader in global relay industry.HONGFA has more than 30 subsidiaries worldwide, and its business covers more than 120 …
WebBAP31 loss-of-function mutations is the cause of 'deafness, dystonia, and central hypomyelination' (DDCH) syndrome, characterized by severe neurological symptoms …
WebNov 7, 2024 · It is demonstrated that BAP31-deletion induces SREBP activation and promotes hepatic lipid accumulation, reduces insulin signaling, impairs glucose/insulin … history of tattoosWebJul 18, 2024 · Identification of BAP31 as a new CTA using SADA method. CTAs expression is limited to male germ cells in healthy adults, but ectopic expression has been observed … history of tattoos as an art formWebBackground BAP31 (B-cell receptor-association protein 31) is a transmembrane protein associated with the endplasmic reticulum (ER) and ER-Golgi intermediates and has been implicated in protein trafficking and apoptosis (1,2).During apoptosis Bap31 is cleaved by caspase-8 at two carboxy-terminal sites which can then direct apoptotic signals between … history of tbiWebJun 9, 2024 · particular, BAP31 is involved in regulating apoptosis mediated by Bcl‑2 and Bcl‑XL (11). The BCAP31 gene is located in the q28 open reading frame of the X chromosome that is 738‑bp in length and encodes 246 amino acids. The molecular weight of the mature BAP31 protein product is 28 KDa (9,10). BAP31 is history of teaching reading in the ukWebAug 26, 2024 · Previously, we reported that B cell receptor associated protein 31 (BAP31) is a positive regulator on T-cells activation. Helper T cells [cluster of differentiation 4+ … history of taylormade driversWebMar 8, 2024 · Bap31 is a polytopic integral protein of the endoplasmic reticulum membrane and a substrate of caspase-8. Bap31 is cleaved within its cytosolic domain, generating pro-apoptotic p20 Bap31. Links? Taxonomy: Opisthokonta: PubMed: 1 link: Protein: Related Protein : Related Structure: Statistics? Accession: cl02219: PSSM Id: 445710: history of tbeWebConditional knockout mice with targeted disruption of BAP31 in adult mouse liver were generated and challenged with a high-fat diet (HFD) for 36 or 96 days, markers of … honda jazz timing belt or chain